Reaction Details Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM50469032
Substrate
n/a
Meas. Tech.
ChEMBL_1802563 (CHEMBL4274855)
Ki
115±n/a nM
Citation
 Zscherp, R; Baumeister, S; Schepmann, D; Wünsch, B Pyridine bioisosteres of potent GluN2B subunit containing NMDA receptor antagonists with benzo[7]annulene scaffold. Eur J Med Chem 157:397-404 (2018) [PubMed]  Article 
Target
Name:
Sigma intracellular receptor 2
Synonyms:
S2r | SGMR2_RAT | Sigma intracellular receptor 2 | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97
Type:
Protein
Mol. Mass.:
20953.88
Organism:
Rattus norvegicus (Rat)
Description:
Q5U3Y7
Residue:
176
Sequence:
MGAVTARRCVEWLLGLYFVSHIPITMFIDLQALLPPELYPQEFSNLLRWYSKEFKDPLMQEPPVWFKSFLFCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAVHTITTLIPILYTILFEDFSKAIAFKGQRPENFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKFEEKRKKK
  
Inhibitor
Name:
BDBM50469032
Synonyms:
CHEMBL4284692
Type:
Small organic molecule
Emp. Form.:
C21H28N2
Mol. Mass.:
308.4604
SMILES:
CN(CCCCc1ccccc1)C1CCc2cccnc2CC1
Structure:
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