Reaction Details Report a problem with these data
Target
LL-diaminopimelate aminotransferase, chloroplastic
Ligand
BDBM50481532
Substrate
n/a
Meas. Tech.
ChEMBL_613320 (CHEMBL1074257)
IC50
33000±n/a nM
Citation
 Fan, C; Clay, MD; Deyholos, MK; Vederas, JC Exploration of inhibitors for diaminopimelate aminotransferase. Bioorg Med Chem 18:2141-2151 (2010) [PubMed]  Article 
Target
Name:
LL-diaminopimelate aminotransferase, chloroplastic
Synonyms:
2.6.1.83 | AGD2 | AGD2 | AtDAP-AT | DAP | DAP-AT | DAP-aminotransferase | DAPAT_ARATH | LL-DAP-aminotransferase | LL-diaminopimelate aminotransferase, chloroplastic | Protein ABERRANT GROWTH AND DEATH 2
Type:
PROTEIN
Mol. Mass.:
50399.19
Organism:
Arabidopsis thaliana
Description:
ChEMBL_109120
Residue:
461
Sequence:
MSSTHQLVSSMISSSSSTFLAPSNFNLRTRNACLPMAKRVNTCKCVATPQEKIEYKTKVSRNSNMSKLQAGYLFPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQLYK
  
Inhibitor
Name:
BDBM50481532
Synonyms:
CHEMBL591735
Type:
Small organic molecule
Emp. Form.:
C27H20N4O3S
Mol. Mass.:
480.538
SMILES:
O=C(Cn1c(\C=C2\C(=O)NC(=S)N(C2=O)c2ccccc2)cc2ccccc12)Nc1ccccc1
Structure:
Search PDB for entries with ligand similarity: