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Target
Protein-glutamine gamma-glutamyltransferase, liver
Ligand
BDBM50481651
Substrate
n/a
Meas. Tech.
ChEMBL_607926 (CHEMBL1066254)
IC50
1400±n/a nM
Citation
 Ozaki, S; Ebisui, E; Hamada, K; Goto, J; Suzuki, AZ; Terauchi, A; Mikoshiba, K Potent transglutaminase inhibitors, aryl beta-aminoethyl ketones. Bioorg Med Chem Lett 20:1141-4 (2010) [PubMed]  Article 
Target
Name:
Protein-glutamine gamma-glutamyltransferase, liver
Synonyms:
2.3.2.13 | Protein-glutamine gamma-glutamyltransferase, liver
Type:
PROTEIN
Mol. Mass.:
49544.80
Organism:
Cavia porcellus
Description:
ChEMBL_109264
Residue:
444
Sequence:
ILDICLMLLDTNPKFLKNAGQDCSRRSRPVYVGRVVSAMVNCNDDQGVLQGRWDNNYSDGVSPMSWIGSVDILRRWKDYGCQRVKYGQCWVFAAVACTVLRCLAIPTRVVTNFNSAHDQNSNLLIEYFRNESGEIEGNKSEMIWNFHSLLGGVVDDQAGPGAWVRGVQALDPTPQEKSEGTYCCGPVPVRAIKEGHLNVKYDAPFVFAEVNADVVNWIRQKDGSLRKSINHLVVGLKISTKSVGRDEREDITHTYKYPEGSEEEREAFVRANHLNKLATKEEAQEETGVAMRIRVGQNMTMGSDFDIFAYITNGTAESHECQLLLCARIVSYNGVLGPVCSTNDLLNLTLDPFSENSIPLHILYEKYGDYLTESNLIKVRGLLIEPAANSYVLAERDIYLENPEIKIRVLGEPKQNRKLIAEVSLKNPLPVPLLGCIFTVEGAG
  
Inhibitor
Name:
BDBM50481651
Synonyms:
CHEMBL597178
Type:
Small organic molecule
Emp. Form.:
C17H20N2O
Mol. Mass.:
268.3535
SMILES:
CCN(CCC(=O)c1ccncc1)Cc1ccccc1
Structure:
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