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Target
Protease
Ligand
BDBM50483482
Substrate
n/a
Meas. Tech.
ChEMBL_728017 (CHEMBL1686815)
IC50
13±n/a nM
Citation
 Nguyen, JT; Kato, K; Kumada, HO; Hidaka, K; Kimura, T; Kiso, Y Maintaining potent HTLV-I protease inhibition without the P3-cap moiety in small tetrapeptidic inhibitors. Bioorg Med Chem Lett 21:1832-7 (2011) [PubMed]  Article 
Target
Name:
Protease
Synonyms:
Protease | prt
Type:
PROTEIN
Mol. Mass.:
13462.60
Organism:
Human T-cell leukemia virus type I
Description:
ChEMBL_118454
Residue:
125
Sequence:
PVIPLDPARRPVIKAQVDTQTSHPKTIEALLDTGADMTVLPIALFSSNTPLKNTSVLGAGGQTQDHFKLTSLPVLIRLPFRTTPIVLTSCLVDTKNNWAIIGRDALQQCQGVLYLPEAKGPPVIL
  
Inhibitor
Name:
BDBM50483482
Synonyms:
CHEMBL3349018
Type:
Small organic molecule
Emp. Form.:
C39H54F3N5O6S
Mol. Mass.:
777.936
SMILES:
CCCC(=O)NC(C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)[C@H](O)C(=O)N1CSC(C)(C)[C@H]1C(=O)NCC(C)(C)C)C(C)(C)C)c1cc(F)c(F)c(F)c1 |r|
Structure:
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