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Target
Protease
Ligand
BDBM50483599
Substrate
n/a
Meas. Tech.
ChEMBL_740706 (CHEMBL1763768)
IC50
10±n/a nM
Citation
 Nguyen, JT; Kato, K; Hidaka, K; Kumada, HO; Kimura, T; Kiso, Y Design and synthesis of several small-size HTLV-I protease inhibitors with different hydrophilicity profiles. Bioorg Med Chem Lett 21:2425-9 (2011) [PubMed]  Article 
Target
Name:
Protease
Synonyms:
Protease | prt
Type:
PROTEIN
Mol. Mass.:
13462.60
Organism:
Human T-cell leukemia virus type I
Description:
ChEMBL_118454
Residue:
125
Sequence:
PVIPLDPARRPVIKAQVDTQTSHPKTIEALLDTGADMTVLPIALFSSNTPLKNTSVLGAGGQTQDHFKLTSLPVLIRLPFRTTPIVLTSCLVDTKNNWAIIGRDALQQCQGVLYLPEAKGPPVIL
  
Inhibitor
Name:
BDBM50483599
Synonyms:
CHEMBL1761460 | KNI-10605
Type:
Small organic molecule
Emp. Form.:
C36H52N6O7S
Mol. Mass.:
712.899
SMILES:
COC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)[C@H](O)C(=O)N1CSC(C)(C)[C@H]1C(=O)NNC(C)(C)C)C(C)(C)C)c1ccccc1 |r|
Structure:
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