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Target
Integrase
Ligand
BDBM50484854
Substrate
n/a
Meas. Tech.
ChEMBL_809660 (CHEMBL2015879)
IC50
110±n/a nM
Citation
 Agapkina, J; Zatsepin, T; Knyazhanskaya, E; Mouscadet, JF; Gottikh, M Structure-Activity Relationship Studies of HIV-1 Integrase Oligonucleotide Inhibitors. ACS Med Chem Lett 2:532-7 (2011) [PubMed]  Article 
Target
Name:
Integrase
Synonyms:
pol
Type:
PROTEIN
Mol. Mass.:
32203.43
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_106649
Residue:
288
Sequence:
FLDGIDKAQEEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGIKQEFGIPYNPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPVWKGPAKLLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED
  
Inhibitor
Name:
BDBM50484854
Synonyms:
CHEMBL2012009
Type:
Small organic molecule
Emp. Form.:
C140H167Br4N36O76P11S
Mol. Mass.:
4262.412
SMILES:
n/a
Structure:
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