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Target
Neuraminidase
Ligand
BDBM50155446
Substrate
n/a
Meas. Tech.
ChEMBL_819002 (CHEMBL2034234)
IC50
110000±n/a nM
Citation
 Dao, TT; Dang, TT; Nguyen, PH; Kim, E; Thuong, PT; Oh, WK Xanthones from Polygala karensium inhibit neuraminidases from influenza A viruses. Bioorg Med Chem Lett 22:3688-92 (2012) [PubMed]  Article 
Target
Name:
Neuraminidase
Synonyms:
NA | NRAM_I33A0
Type:
PROTEIN
Mol. Mass.:
49687.56
Organism:
Influenza A virus
Description:
ChEMBL_1347422
Residue:
453
Sequence:
MNPNQKIITIGSICMVVGIISLILQIGNIISIWISHSIQTGNQNHTGICNQGIITYNVVAGQDSTSVILTGNSSLCPIRGWAIHSKDNGIRIGSKGDVFVIREPFISCSHLECRTFFLTQGALLNDKHSNGTVKDRSPYRALMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGISGPDNGAVAVLKYNGIITETIKSWRKKILRTQESECTCVNGSCFTIMTDGPSNGLASYKIFKIEKGKVTKSIELNAPNSHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYQIGYICSGVFGDNPRPKDGPGSCGPVSADGANGVKGFSYRYGNGVWIGRTKSDSSRHGFEMIWDPNGWTETDSRFSVRQDVVAMTDRSGYSGSFVQHPELTGLDCMRPCFWVELIRGRPEEETIWTSGSIISFCGVNSDTVDWSWPDGAELPFTIDK
  
Inhibitor
Name:
BDBM50155446
Synonyms:
1,3,7-Trihydroxy xanthone (3) | 1,3,7-Trihydroxy-xanthen-9-one | 1,3,7-trihydroxy-9H-xanthen-9-one | CHEMBL361025
Type:
Small organic molecule
Emp. Form.:
C13H8O5
Mol. Mass.:
244.1996
SMILES:
Oc1ccc2oc3cc(O)cc(O)c3c(=O)c2c1
Structure:
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