Reaction Details Report a problem with these data
Target
Histamine H2 receptor
Ligand
BDBM50103506
Substrate
n/a
Meas. Tech.
ChEMBL_910821 (CHEMBL3058111)
Kd
63±n/a nM
Citation
  TBA Med Chem Res 13:78-87 (2004)    Article 
Target
Name:
Histamine H2 receptor
Synonyms:
Gastric receptor I | H2R | HISTAMINE H2 | HRH2 | HRH2_HUMAN | Histamine H2 receptor | Histamine H2-Gs alpha S
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40115.31
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
359
Sequence:
MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTEVTAPQGATDR
  
Inhibitor
Name:
BDBM50103506
Synonyms:
Ranitidine | Tritec | Zantac
Type:
Small organic molecule
Emp. Form.:
C13H22N4O3S
Mol. Mass.:
314.404
SMILES:
CNC(NCCSCc1ccc(CN(C)C)o1)=C[N+]([O-])=O
Structure:
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