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Target
NADH-ubiquinone oxidoreductase chain 1
Ligand
BDBM50488035
Substrate
n/a
Meas. Tech.
ChEMBL_919598 (CHEMBL3083635)
IC50
4400±n/a nM
Citation
 Cantín, A; López-Gresa, MP; González, MC; Moya, P; Miranda, MA; Primo, J; Romero, V; Peris, E; Estornell, E Novel inhibitors of the mitochondrial respiratory chain: oximes and pyrrolines isolated from Penicillium brevicompactum and synthetic analogues. J Agric Food Chem 53:8296-301 (2005) [PubMed]  Article 
Target
Name:
NADH-ubiquinone oxidoreductase chain 1
Synonyms:
MT-ND1 | MTND1 | NADH Oxidase | NADH-ubiquinone oxidoreductase | NADH-ubiquinone oxidoreductase chain 1 | NADH1 | ND1 | NU1M_BOVIN
Type:
Protein
Mol. Mass.:
35672.63
Organism:
Bovine
Description:
P03887
Residue:
318
Sequence:
MFMINILMLIIPILLAVAFLTLVERKVLGYMQLRKGPNVVGPYGLLQPIADAIKLFIKEPLRPATSSASMFILAPIMALGLALTMWIPLPMPYPLINMNLGVLFMLAMSSLAVYSILWSGWASNSKYALIGALRAVAQTISYEVTLAIILLSVLLMSGSFTLSTLITTQEQMWLILPAWPLAMMWFISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFALFFMAEYANIIMMNIFTAILFLGTSHNPHMPELYTINFTIKSLLLTMSFLWIRASYPRFRYDQLMHLLWKNFLPLTLALCMWHVSLPILTSGIPPQT
  
Inhibitor
Name:
BDBM50488035
Synonyms:
CHEMBL2269864
Type:
Small organic molecule
Emp. Form.:
C22H23NO3
Mol. Mass.:
349.4229
SMILES:
CC(C(=O)C(C)c1cccc(Oc2ccccc2)c1)C(=O)N1CCC=C1 |c:26|
Structure:
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