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Target
RNA-directed RNA polymerase
Ligand
BDBM50191522
Substrate
n/a
Meas. Tech.
ChEMBL_932863 (CHEMBL3074361)
IC50
19900000±n/a nM
Citation
  TBA Med Chem Res 22:1866-1883 (2013)    Article 
Target
Name:
RNA-directed RNA polymerase
Synonyms:
2.7.7.48 | NS5B | RNA-directed RNA polymerase
Type:
PROTEIN
Mol. Mass.:
13231.83
Organism:
Hepatitis C virus genotype 1
Description:
ChEMBL_106647
Residue:
121
Sequence:
RCFDSTVTENDIRVEESIYQCCDLDPQARVAIKSLTERLYVGGPFTNSRGENCGYRRCRASGVLTTRCGNTLTCYMKAQAACRAARLRDCTMLVSGDDLVVICESAGAQEDAASLRAFTEA
  
Inhibitor
Name:
BDBM50191522
Synonyms:
1-cyclohexyl-2-[4-(4,4'-dichlorobiphenyl-2-ylmethoxy)phenyl]-1H-benzimidazole-5-carboxylic acid | CHEMBL211507
Type:
Small organic molecule
Emp. Form.:
C33H28Cl2N2O3
Mol. Mass.:
571.493
SMILES:
OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccc(OCc2cc(Cl)ccc2-c2ccc(Cl)cc2)cc1
Structure:
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