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Target
Peroxisome proliferator-activated receptor delta
Ligand
BDBM50492978
Substrate
n/a
Meas. Tech.
ChEMBL_976992 (CHEMBL2416516)
IC50
28±n/a nM
Citation
 Ban, S; Ueda, Y; Ohashi, M; Matsuno, K; Ikeda, M; Kato, N; Miyachi, H Peroxisome proliferator-activated receptor delta antagonists inhibit hepatitis C virus RNA replication. Bioorg Med Chem Lett 23:4774-8 (2013) [PubMed]  Article 
Target
Name:
Peroxisome proliferator-activated receptor delta
Synonyms:
NR1C2 | NUC1 | NUCI | Nuclear hormone receptor 1 | Nuclear receptor subfamily 1 group C member 2 | PPAR delta | PPAR-beta | PPARB | PPARD | PPARD_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor beta | Peroxisome proliferator-activated receptor delta
Type:
Enzyme
Mol. Mass.:
49910.45
Organism:
Homo sapiens (Human)
Description:
Q03181
Residue:
441
Sequence:
MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQMGCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKKNRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSKHIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRIKKTETETSLHPLLQEIYKDMY
  
Inhibitor
Name:
BDBM50492978
Synonyms:
CHEMBL2413228
Type:
Small organic molecule
Emp. Form.:
C25H22F3NO4
Mol. Mass.:
457.4417
SMILES:
CCOc1ccc(cc1CNC(=O)c1ccc(cc1)C(F)(F)F)-c1ccc(cc1C)C(O)=O
Structure:
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