Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50494098
Substrate
n/a
Meas. Tech.
ChEMBL_990336 (CHEMBL2445749)
Ki
35±n/a nM
Citation
 Petrov, RR; Knight, L; Chen, SR; Wager-Miller, J; McDaniel, SW; Diaz, F; Barth, F; Pan, HL; Mackie, K; Cavasotto, CN; Diaz, P Mastering tricyclic ring systems for desirable functional cannabinoid activity. Eur J Med Chem 69:881-907 (2013) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50494098
Synonyms:
CHEMBL2441256
Type:
Small organic molecule
Emp. Form.:
C23H29N3O
Mol. Mass.:
363.4959
SMILES:
CCCCCn1c2ccccc2c2cc(ccc12)C(=O)N1CCN(C)CC1
Structure:
Search PDB for entries with ligand similarity: