Reaction Details Report a problem with these data
Target
P2Y purinoceptor 6
Ligand
BDBM50496856
Substrate
n/a
Meas. Tech.
ChEMBL_1330934 (CHEMBL3224914)
EC50
19±n/a nM
Citation
 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Kozma, E; Costanzi, S; Squarcialupi, L; Balasubramanian, R; Maruoka, H; Jacobson, KA 4-Alkyloxyimino-cytosine nucleotides: tethering approaches to molecular probes for the P2Y Medchemcomm 4:1156-1165 (2013) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 6
Synonyms:
P2RY6 | P2RY6_HUMAN | P2Y purinoceptor 6 | P2Y6 | Pyrimidinergic receptor P2Y6
Type:
PROTEIN
Mol. Mass.:
36452.29
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1511151
Residue:
328
Sequence:
MEWDNGTGQALGLPPTTCVYRENFKQLLLPPVYSAVLAAGLPLNICVITQICTSRRALTRTAVYTLNLALADLLYACSLPLLIYNYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRAAWLVCVAVWLAVTTQCLPTAIFAATGIQRNRTVCYDLSPPALATHYMPYGMALTVIGFLLPFAALLACYCLLACRLCRQDGPAEPVAQERRGKAARMAVVVAAAFAISFLPFHITKTAYLAVRSTPGVPCTVLEAFAAAYKGTRPFASANSVLDPILFYFTQKKFRRRPHELLQKLTAKWQRQGR
  
Inhibitor
Name:
BDBM50496856
Synonyms:
CHEMBL3220047
Type:
Small organic molecule
Emp. Form.:
C16H20IN3O12P2
Mol. Mass.:
635.1949
SMILES:
O[C@@H]1[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cc\c(=N\OCc2cccc(I)c2)[nH]c1=O |r|
Structure:
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