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Target
Neuraminidase
Ligand
BDBM50497287
Substrate
n/a
Meas. Tech.
ChEMBL_1433025 (CHEMBL3385173)
IC50
>1000000±n/a nM
Citation
 El-Deeb, IM; Guillon, P; Winger, M; Eveno, T; Haselhorst, T; Dyason, JC; von Itzstein, M Exploring human parainfluenza virus type-1 hemagglutinin-neuraminidase as a target for inhibitor discovery. J Med Chem 57:7613-23 (2014) [PubMed]  Article 
Target
Name:
Neuraminidase
Synonyms:
NA | NRAM_I33A0
Type:
PROTEIN
Mol. Mass.:
49687.56
Organism:
Influenza A virus
Description:
ChEMBL_1347422
Residue:
453
Sequence:
MNPNQKIITIGSICMVVGIISLILQIGNIISIWISHSIQTGNQNHTGICNQGIITYNVVAGQDSTSVILTGNSSLCPIRGWAIHSKDNGIRIGSKGDVFVIREPFISCSHLECRTFFLTQGALLNDKHSNGTVKDRSPYRALMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGISGPDNGAVAVLKYNGIITETIKSWRKKILRTQESECTCVNGSCFTIMTDGPSNGLASYKIFKIEKGKVTKSIELNAPNSHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYQIGYICSGVFGDNPRPKDGPGSCGPVSADGANGVKGFSYRYGNGVWIGRTKSDSSRHGFEMIWDPNGWTETDSRFSVRQDVVAMTDRSGYSGSFVQHPELTGLDCMRPCFWVELIRGRPEEETIWTSGSIISFCGVNSDTVDWSWPDGAELPFTIDK
  
Inhibitor
Name:
BDBM50497287
Synonyms:
CHEMBL3330707
Type:
Small organic molecule
Emp. Form.:
C12H19N4NaO7
Mol. Mass.:
354.2916
SMILES:
[Na;v0+].[H][C@]1([#8]-[#6](=[#6]-[#6@H](-[#7]-[#6](-[#7])=[#7])-[#6@H]1-[#7]-[#6](-[#6])=O)-[#6](-[#8-])=O)[#6@H](-[#8])-[#6@H](-[#8])-[#6]-[#8] |r,c:3|
Structure:
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