Reaction Details Report a problem with these data
Target
D(3) dopamine receptor
Ligand
BDBM50500111
Substrate
n/a
Meas. Tech.
ChEMBL_1541795 (CHEMBL3742609)
Ki
810±n/a nM
Citation
 Cao, Y; Min, C; Acharya, S; Kim, KM; Cheon, SH Design, synthesis and evaluation of bitopic arylpiperazinephenyl-1,2,4-oxadiazoles as preferential dopamine D3 receptor ligands. Bioorg Med Chem 24:191-200 (2016) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50500111
Synonyms:
CHEMBL3740360
Type:
Small organic molecule
Emp. Form.:
C22H25Cl2N5O
Mol. Mass.:
446.373
SMILES:
Clc1ccc(N2CCN(CCCCNc3noc(n3)-c3ccccc3)CC2)c(Cl)c1
Structure:
Search PDB for entries with ligand similarity: