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Target
5-hydroxytryptamine receptor 4
Ligand
BDBM50058171
Substrate
n/a
Meas. Tech.
ChEMBL_3337 (CHEMBL619037)
Ki
14.5±n/a nM
Citation
 Soulier, JL; Yang, D; Brémont, B; Croci, T; Guzzi, U; Langlois, M Arylcarbamate derivatives of 1-piperidineethanol as potent ligands for 5-HT4 receptors. J Med Chem 40:1755-61 (1997) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 4
Synonyms:
5-HT-4 | 5-HT4 | 5-HT4L | 5-HT4S | 5-hydroxytryptamine receptor 4 | 5HT4R_RAT | Htr4 | Serotonin (5-HT) receptor | Serotonin 4 (5-HT4) receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46117.31
Organism:
RAT
Description:
5-HT4 HTR4 RAT::Q62758
Residue:
406
Sequence:
MDRLDANVSSNEGFGSVEKVVLLTFFAMVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVNAFGAIELVQDIWFYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPMFISFLPIMQGWNNIGIVDVIEKRKFNHNSNSTFCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQTADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEKVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPVIRRPQDNDLEDSCSLKRSQS
  
Inhibitor
Name:
BDBM50058171
Synonyms:
(4-Amino-5-chloro-2-methoxy-phenyl)-carbamic acid 2-azepan-1-yl-ethyl ester | CHEMBL50852
Type:
Small organic molecule
Emp. Form.:
C16H24ClN3O3
Mol. Mass.:
341.833
SMILES:
COc1cc(N)c(Cl)cc1NC(=O)OCCN1CCCCCC1
Structure:
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