Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50063184
Substrate
n/a
Meas. Tech.
ChEMBL_29121 (CHEMBL642255)
Ki
102±n/a nM
Citation
 Betti, L; Biagi, G; Giannaccini, G; Giorgi, I; Livi, O; Lucacchini, A; Manera, C; Scartoni, V Novel 3-aralkyl-7-(amino-substituted)-1,2,3-triazolo[4,5-d]pyrimidines with high affinity toward A1 adenosine receptors. J Med Chem 41:668-73 (1998) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_BOVIN | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36602.99
Organism:
BOVINE
Description:
ADENOSINE 0 BOVINE::P28190
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPRTYFHTCLKVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAVVAITGCWILSFVVGLTPMFGWNNLSAVERDWLANGSVGEPVIECQFEKVISMEYMVYFNFFVWVLPPLLLMVLIYMEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHMPRILIYIAIFLSHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPVDEDAPAERPDD
  
Inhibitor
Name:
BDBM50063184
Synonyms:
CHEMBL161051 | [3-(2-Chloro-benzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-(3-methyl-cyclohexyl)-amine
Type:
Small organic molecule
Emp. Form.:
C18H21ClN6
Mol. Mass.:
356.853
SMILES:
CC1CCCC(C1)Nc1ncnc2n(Cc3ccccc3Cl)nnc12
Structure:
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