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Target
Serine protease 1
Ligand
BDBM50063704
Substrate
n/a
Meas. Tech.
ChEMBL_212344 (CHEMBL818267)
IC50
4500±n/a nM
Citation
 Hays, SJ; Caprathe, BW; Gilmore, JL; Amin, N; Emmerling, MR; Michael, W; Nadimpalli, R; Nath, R; Raser, KJ; Stafford, D; Watson, D; Wang, K; Jaen, JC 2-amino-4H-3,1-benzoxazin-4-ones as inhibitors of C1r serine protease. J Med Chem 41:1060-7 (1998) [PubMed]  Article 
Target
Name:
Serine protease 1
Synonyms:
Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I
Type:
Enzyme
Mol. Mass.:
25790.52
Organism:
Bos taurus (bovine)
Description:
P00760
Residue:
246
Sequence:
MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN
  
Inhibitor
Name:
BDBM50063704
Synonyms:
2-[(2-Iodo-phenyl)-methyl-amino]-benzo[d][1,3]oxazin-4-one | CHEMBL10768
Type:
Small organic molecule
Emp. Form.:
C15H11IN2O2
Mol. Mass.:
378.1645
SMILES:
CN(c1nc2ccccc2c(=O)o1)c1ccccc1I
Structure:
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