Reaction Details Report a problem with these data
Target
Growth factor receptor-bound protein 2
Ligand
BDBM50066510
Substrate
n/a
Meas. Tech.
ChEMBL_72353 (CHEMBL686440)
IC50
64±n/a nM
Citation
 Furet, P; Gay, B; Caravatti, G; García-Echeverría, C; Rahuel, J; Schoepfer, J; Fretz, H Structure-based design and synthesis of high affinity tripeptide ligands of the Grb2-SH2 domain. J Med Chem 41:3442-9 (1998) [PubMed]  Article 
Target
Name:
Growth factor receptor-bound protein 2
Synonyms:
ASH | GRB2 | GRB2 adapter protein | GRB2_HUMAN | Grb2-SH2 | Growth factor receptor-bound protein 2
Type:
Protein
Mol. Mass.:
25205.04
Organism:
Homo sapiens (Human)
Description:
P62993
Residue:
217
Sequence:
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
  
Inhibitor
Name:
BDBM50066510
Synonyms:
2-{10-Amino-11-[4-(diacetoxy-phosphoryloxy)-phenyl]-7,9-dioxo-undecylamino}-N-(3-naphthalen-1-yl-propyl)-succinamic acid | CHEMBL325621
Type:
Small organic molecule
Emp. Form.:
C38H48N3O11P
Mol. Mass.:
753.775
SMILES:
CC(=O)OP(=O)(OC(C)=O)Oc1ccc(CC(N)C(=O)CC(=O)CCCCCCNC(CC(=O)NCCCc2cccc3ccccc23)C(O)=O)cc1
Structure:
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