Reaction Details Report a problem with these data
Target
Serine protease 1
Ligand
BDBM50071724
Substrate
n/a
Meas. Tech.
ChEBML_212376
Ki
17100±n/a nM
Citation
 Lee, K; Jung, WH; Park, CW; Hong, CY; Kim, IC; Kim, S; Oh, YS; Kwon, OH; Lee, SH; Park, HD; Kim, SW; Lee, YH; Yoo, YJ Benzylamine-based selective and orally bioavailable inhibitors of thrombin. Bioorg Med Chem Lett 8:2563-8 (1999) [PubMed]  Article 
Target
Name:
Serine protease 1
Synonyms:
Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I
Type:
Enzyme
Mol. Mass.:
25790.52
Organism:
Bos taurus (bovine)
Description:
P00760
Residue:
246
Sequence:
MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN
  
Inhibitor
Name:
BDBM50071724
Synonyms:
(S)-3-(4-Aminomethyl-phenyl)-N-cyclopentyl-2-(5-dimethylamino-naphthalene-1-sulfonylamino)-N-methyl-propionamide | CHEMBL421880
Type:
Small organic molecule
Emp. Form.:
C28H36N4O3S
Mol. Mass.:
508.675
SMILES:
CN(C)c1cccc2c(cccc12)S(=O)(=O)N[C@@H](Cc1ccc(CN)cc1)C(=O)N(C)C1CCCC1
Structure:
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