Reaction Details Report a problem with these data
Target
Frizzled-7
Ligand
BDBM50519334
Substrate
n/a
Meas. Tech.
ChEMBL_1874882 (CHEMBL4376171)
Kd
0.190000±n/a nM
Citation
 Hansen, S; Nile, AH; Mehta, SC; Fuhrmann, J; Hannoush, RN Lead Optimization Yields High Affinity Frizzled 7-Targeting Peptides That Modulate  J Med Chem 62:7739-7750 (2019) [PubMed]  Article 
Target
Name:
Frizzled-7
Synonyms:
FZD7 | FZD7_HUMAN | Frizzled-7 | Fz-7 | FzE3 | hFz7
Type:
PROTEIN
Mol. Mass.:
63630.03
Organism:
Homo sapiens
Description:
ChEMBL_109743
Residue:
574
Sequence:
MRDPGAAAPLSSLGLCALVLALLGALSAGAGAQPYHGEKGISVPDHGFCQPISIPLCTDIAYNQTILPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLDQAIPPCRSLCERARQGCEALMNKFGFQWPERLRCENFPVHGAGEICVGQNTSDGSGGPGGGPTAYPTAPYLPDLPFTALPPGASDGRGRPAFPFSCPRQLKVPPYLGYRFLGERDCGAPCEPGRANGLMYFKEEERRFARLWVGVWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYFMVAVAHVAGFLLEDRAVCVERFSDDGYRTVAQGTKKEGCTILFMVLYFFGMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQVDGDLLSGVCYVGLSSVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVLACYFYEQAFREHWERTWLLQTCKSYAVPCPPGHFPPMSPDFTVFMIKYLMTMIVGITTGFWIWSGKTLQSWRRFYHRLSHSSKGETAV
  
Inhibitor
Name:
BDBM50519334
Synonyms:
CHEMBL4587027
Type:
Small organic molecule
Emp. Form.:
C144H190N32O42S2Se2
Mol. Mass.:
3263.29
SMILES:
n/a
Structure:
Search PDB for entries with ligand similarity: