Reaction Details Report a problem with these data
Target
Protease
Ligand
BDBM50520750
Substrate
n/a
Meas. Tech.
ChEMBL_1882113 (CHEMBL4383612)
Ki
1.1±n/a nM
Citation
Ghosh, AK; Jadhav, RD; Simpson, H; Kovela, S; Osswald, H; Agniswamy, J; Wang, YF; Hattori, SI; Weber, IT; Mitsuya, H Design, synthesis, and X-ray studies of potent HIV-1 protease inhibitors incorporating aminothiochromane and aminotetrahydronaphthalene carboxamide derivatives as the P2 ligands. Eur J Med Chem 160:171-182 (2018) [PubMed] Article
More Info.:
Target
Name:
Protease
Synonyms:
n/a
Type:
Enzyme
Mol. Mass.:
10904.79
Organism:
Human immunodeficiency virus 1 (HIV-1)
Description:
Q9YQ12
Residue:
99
Sequence:
PQITLWQRPFVTIKIEGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQIVIEICGKKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF