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Target
Somatostatin receptor type 2
Ligand
BDBM50077293
Substrate
n/a
Meas. Tech.
ChEMBL_200687 (CHEMBL807098)
Ki
37±n/a nM
Citation
 Hocart, SJ; Jain, R; Murphy, WA; Taylor, JE; Coy, DH Highly potent cyclic disulfide antagonists of somatostatin. J Med Chem 42:1863-71 (1999) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 2
Synonyms:
SOMATOSTATIN SST2 | SRIF-1 | SS-2-R | SS2-R | SS2R | SSR2_HUMAN | SSTR2 | Somatostatin receptor type 2 (SSTR2)
Type:
Enzyme
Mol. Mass.:
41344.94
Organism:
Homo sapiens (Human)
Description:
P30874
Residue:
369
Sequence:
MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFVVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVLTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI
  
Inhibitor
Name:
BDBM50077293
Synonyms:
10-(4-Amino-butyl)-19-(2-amino-3-naphthalen-2-yl-propionylamino)-13-(1H-indol-3-ylmethyl)-7-isopropyl-6,9,12,15,18-pentaoxo-16-pyridin-3-ylmethyl-1,2-dithia-5,8,11,14,17-pentaaza-cycloicosane-4-carboxylic acid (1-carbamoyl-2,2-diphenyl-ethyl)-amide | CHEMBL412859
Type:
Small organic molecule
Emp. Form.:
C64H74N12O8S2
Mol. Mass.:
1203.478
SMILES:
CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@H](CSSC[C@@H](NC1=O)C(=O)N[C@@H](C(c1ccccc1)c1ccccc1)C(N)=O)NC(=O)[C@@H](N)Cc1ccc2ccccc2c1
Structure:
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