Reaction Details Report a problem with these data
Target
Scytalone dehydratase
Ligand
BDBM50078273
Substrate
n/a
Meas. Tech.
ChEBML_199522
Ki
7.5±n/a nM
Citation
 Jordan, DB; Lessen, TA; Wawrzak, Z; Bisaha, JJ; Gehret, TC; Hansen, SL; Schwartz, RS; Basarab, GS Design of scytalone dehydratase inhibitors as rice blast fungicides: (N-phenoxypropyl)-carboxamides. Bioorg Med Chem Lett 9:1607-12 (1999) [PubMed]  Article 
Target
Name:
Scytalone dehydratase
Synonyms:
SCYD_MAGO7 | SDH1 | Scytalone dehydratase
Type:
PROTEIN
Mol. Mass.:
20248.63
Organism:
Rice blast fungus
Description:
ChEMBL_199536
Residue:
172
Sequence:
MGSQVQKSDEITFSDYLGLMTCVYEWADSYDSKDWDRLRKVIAPTLRIDYRSFLDKLWEAMPAEEFVGMVSSKQVLGDPTLRTQHFIGGTRWEKVSEDEVIGYHQLRVPHQRYKDTTMKEVTMKGHAHSANLHWYKKIDGVWKFAGLKPDIRWGEFDFDRIFEDGRETFGDK
  
Inhibitor
Name:
BDBM50078273
Synonyms:
(R)-2,2-Dichloro-1-ethyl-3-methyl-cyclopropanecarboxylic acid (2-phenoxy-ethyl)-amide | CHEMBL41569
Type:
Small organic molecule
Emp. Form.:
C15H19Cl2NO2
Mol. Mass.:
316.223
SMILES:
CC[C@@]1(C(C)C1(Cl)Cl)C(=O)NCCOc1ccccc1
Structure:
Search PDB for entries with ligand similarity: