Reaction Details Report a problem with these data
Target
Transthyretin
Ligand
BDBM50197883
Substrate
n/a
Meas. Tech.
ChEMBL_1902571 (CHEMBL4404793)
Kd
2800±n/a nM
Citation
Cotrina, EY; Gimeno, A; Llop, J; Jiménez-Barbero, J; Quintana, J; Valencia, G; Cardoso, I; Prohens, R; Arsequell, G Calorimetric Studies of Binary and Ternary Molecular Interactions between Transthyretin, A? Peptides, and Small-Molecule Chaperones toward an Alternative Strategy for Alzheimer's Disease Drug Discovery. J Med Chem 63:3205-3214 (2020) [PubMed] Article
More Info.:
Target
Name:
Transthyretin
Synonyms:
ATTR | PALB | Prealbumin | TBPA | TTHY_HUMAN | TTR | Transthyretin (TTR)
Type:
Enzyme
Mol. Mass.:
15884.31
Organism:
Human
Description:
P02766
Residue:
147
Sequence:
MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE