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Target
5-hydroxytryptamine receptor 2A
Ligand
BDBM50088871
Substrate
n/a
Meas. Tech.
ChEMBL_2307 (CHEMBL617514)
Ki
794±n/a nM
Citation
 Isaac, M; Slassi, A; O'Brien, A; Edwards, L; MacLean, N; Bueschkens, D; Lee, DK; McCallum, K; De Lannoy, I; Demchyshyn, L; Kamboj, R Pyrrolo[3,2,1-ij]quinoline derivatives, a 5-HT2c receptor agonist with selectivity over the 5-HT2a receptor: potential therapeutic applications for epilepsy and obesity. Bioorg Med Chem Lett 10:919-21 (2000) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 2A
Synonyms:
5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_HUMAN | HTR2 | HTR2A | Serotonin receptor 2A
Type:
undefined
Mol. Mass.:
52607.65
Organism:
Homo sapiens (Human)
Description:
P28223
Residue:
471
Sequence:
MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV
  
Inhibitor
Name:
BDBM50088871
Synonyms:
2-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-1-ethanamine | CHEMBL171774
Type:
Small organic molecule
Emp. Form.:
C13H16N2
Mol. Mass.:
200.2795
SMILES:
NCCc1cn2CCCc3cccc1c23
Structure:
Search PDB for entries with ligand similarity: