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Target
Muscarinic acetylcholine receptor M2
Ligand
BDBM50064609
Substrate
n/a
Meas. Tech.
ChEMBL_139769 (CHEMBL747479)
Ki
7±n/a nM
Citation
 Daly, JW; Gupta, TH; Padgett, WL; Pei, XF 6beta-Acyloxy(nor)tropanes: affinities for antagonist/agonist binding sites on transfected and native muscarinic receptors. J Med Chem 43:2514-22 (2000) [PubMed]  Article 
Target
Name:
Muscarinic acetylcholine receptor M2
Synonyms:
ACM2_HUMAN | CHRM2 | Cholinergic, muscarinic M2 | Muscarinic acetylcholine receptor M2 and M4 | Muscarinic acetylcholine receptor M2 and M5 | RecName: Full=Muscarinic acetylcholine receptor M2
Type:
GPCR
Mol. Mass.:
51730.61
Organism:
Homo sapiens (Human)
Description:
P08172
Residue:
466
Sequence:
MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
  
Inhibitor
Name:
BDBM50064609
Synonyms:
6-acetoxy-8-azonia-bicyclo[3.2.1]octane | Acetic acid 8-aza-bicyclo[3.2.1]oct-6-yl ester | CHEMBL64000
Type:
Small organic molecule
Emp. Form.:
C9H15NO2
Mol. Mass.:
169.2209
SMILES:
CC(=O)OC1CC2CCCC1N2 |TLB:3:4:11:9.8.7|
Structure:
Search PDB for entries with ligand similarity: