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Target
Mu-type opioid receptor
Ligand
BDBM50535168
Substrate
n/a
Meas. Tech.
ChEMBL_1929931 (CHEMBL4433107)
Ki
1.1±n/a nM
Citation
 Rosse, G Treatment of Pain with Spirocylic Cyclohexane Derivatives Having Dual Specificity for ORL-1 and ?-Opioid Receptors. ACS Med Chem Lett 7:822-3 (2016) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Human
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50535168
Synonyms:
CHEMBL4454146
Type:
Small organic molecule
Emp. Form.:
C21H34N2S
Mol. Mass.:
346.573
SMILES:
CN(C)C1(CCC2(CCN(CC3CCCC3)C2)CC1)c1cccs1 |(27.46,-15.05,;25.97,-14.66,;25.55,-13.17,;24.88,-15.76,;24.1,-17.09,;22.57,-17.08,;21.81,-15.75,;20.78,-14.58,;19.35,-15.2,;19.5,-16.75,;18.34,-17.77,;16.87,-17.28,;16.41,-15.82,;14.86,-15.8,;14.37,-17.27,;15.61,-18.19,;21.01,-17.09,;22.57,-14.42,;24.11,-14.43,;25.97,-16.85,;27.48,-16.61,;28.18,-17.98,;27.1,-19.07,;25.73,-18.37,)|
Structure:
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