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Target
Neuraminidase
Ligand
BDBM96228
Substrate
n/a
Meas. Tech.
ChEMBL_1983495 (CHEMBL4616901)
IC50
37500±n/a nM
Citation
 Chintakrindi, AS; Gohil, DJ; Chowdhary, AS; Kanyalkar, MA Design, synthesis and biological evaluation of substituted flavones and aurones as potential anti-influenza agents. Bioorg Med Chem 28:0 (2020) [PubMed]  Article 
Target
Name:
Neuraminidase
Synonyms:
Influenza A Virus Neuraminidase | NA | NRAM_I34A1 | Neuraminidase | Neuraminidase A
Type:
Enzyme
Mol. Mass.:
50124.14
Organism:
Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(H1N1))
Description:
P03468
Residue:
454
Sequence:
MNPNQKIITIGSICLVVGLISLILQIGNIISIWISHSIQTGSQNHTGICNQNIITYKNSTWVKDTTSVILTGNSSLCPIRGWAIYSKDNSIRIGSKGDVFVIREPFISCSHLECRTFFLTQGALLNDKHSNGTVKDRSPYRALMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGISGPDNGAVAVLKYNGIITETIKSWRKKILRTQESECACVNGSCFTIMTDGPSDGLASYKIFKIEKGKVTKSIELNAPNSHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYQIGYICSGVFGDNPRPEDGTGSCGPVYVDGANGVKGFSYRYGNGVWIGRTKSHSSRHGFEMIWDPNGWTETDSKFSVRQDVVAMTDWSGYSGSFVQHPELTGLDCMRPCFWVELIRGRPKEKTIWTSASSISFCGVNSDTVDWSWPDGAELPFSIDK
  
Inhibitor
Name:
BDBM96228
Synonyms:
(2Z)-2-[(4-methoxyphenyl)methylidene]-1-benzofuran-3-one | (2Z)-2-[(4-methoxyphenyl)methylidene]-3-benzofuranone | (2Z)-2-p-anisylidenecoumaran-3-one | MLS002473405 | SMR001397496 | cid_642384
Type:
Small organic molecule
Emp. Form.:
C16H12O3
Mol. Mass.:
252.2647
SMILES:
COc1ccc(\C=C2/Oc3ccccc3C2=O)cc1
Structure:
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