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Target
Fusion glycoprotein F0
Ligand
BDBM50542655
Substrate
n/a
Meas. Tech.
ChEMBL_1987321 (CHEMBL4620868)
EC50
32±n/a nM
Citation
 Vendeville, S; Tahri, A; Hu, L; Demin, S; Cooymans, L; Vos, A; Kwanten, L; Van den Berg, J; Battles, MB; McLellan, JS; Koul, A; Raboisson, P; Roymans, D; Jonckers, THM Discovery of 3-({5-Chloro-1-[3-(methylsulfonyl)propyl]-1 J Med Chem 63:8046-8058 (2020) [PubMed]  Article 
Target
Name:
Fusion glycoprotein F0
Synonyms:
F | Fusion glycoprotein F0
Type:
PROTEIN
Mol. Mass.:
63485.30
Organism:
Human respiratory syncytial virus
Description:
ChEMBL_106144
Residue:
574
Sequence:
MELPILKANAITTILAAVTFCFASSQNITEEFYQSTCSAVSKGYLSALRTGWYTSVITIELSNIKENKCNGTDAKVKLMKQELDKYKNAVTELQLLMQSTPAANNRARRELPRFMNYTLNNTKKTNVTLSKKRKRRFLGFLLGVGSAIASGIAVSKVLHLEGEVNKIKSALLSTNKAVVSLSNGVSVLTSKVLDLKNYIDKQLLPIVNKQSCRISNIETVIEFQQKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMSNNVQIVRQQSYSIMSIIKEEVLAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNICLTRTDRGWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLTLPSEVNLCNVDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKTKCTASNKNRGIIKTFSNGCDYVSNKGVDTVSVGNTLYYVNKQEGKSLYVKGEPIINFYDPLVFPSDEFDASISQVNEKINQSLAFIRKSDELLHNVNAGKSTTNIMITTIIIVIIVILLSLIAVGLLLYCKARSTPVTLSKDQLSGINNIAFSN
  
Inhibitor
Name:
BDBM50542655
Synonyms:
CHEMBL4646152
Type:
Small organic molecule
Emp. Form.:
C22H24ClN5O3S
Mol. Mass.:
473.976
SMILES:
CS(=O)(=O)CCCn1c(Cn2c3cnccc3n(C3CNC3)c2=O)cc2cc(Cl)ccc12
Structure:
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