Reaction Details Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM50543312
Substrate
n/a
Meas. Tech.
ChEMBL_1988879 (CHEMBL4622426)
Ki
985±n/a nM
Citation
 Greenfield, DA; Schmidt, HR; Skiba, MA; Mandler, MD; Anderson, JR; Sliz, P; Kruse, AC Virtual Screening for Ligand Discovery at the ? ACS Med Chem Lett 11:1555-1561 (2020) [PubMed]  Article 
Target
Name:
Sigma intracellular receptor 2
Synonyms:
MAC30 | Meningioma-associated protein 30 | S2R | SGMR2_HUMAN | Sigma-2 receptor | Sigma2 receptor | TMEM97 | Transmembrane protein 97
Type:
Protein
Mol. Mass.:
20857.20
Organism:
Human
Description:
Q5BJF2
Residue:
176
Sequence:
MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK
  
Inhibitor
Name:
BDBM50543312
Synonyms:
CHEMBL4648233
Type:
Small organic molecule
Emp. Form.:
C18H15Cl2F2N3
Mol. Mass.:
382.235
SMILES:
Cc1nn(c(Cl)c1CNCc1cc(F)cc(F)c1)-c1ccccc1Cl
Structure:
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