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Target
Protein FosB
Ligand
BDBM50544060
Substrate
n/a
Meas. Tech.
ChEMBL_1991494 (CHEMBL4625229)
IC50
>100000±n/a nM
Citation
 Li, Y; Liu, Z; Aglyamova, G; Chen, J; Chen, H; Bhandari, M; White, MA; Rudenko, G; Zhou, J Discovery of phenanthridine analogues as novel chemical probes disrupting the binding of DNA to ?FosB homodimers and ?FosB/JunD heterodimers. Bioorg Med Chem Lett 30:0 (2020) [PubMed]  Article 
Target
Name:
Protein FosB
Synonyms:
FOSB | FOSB_HUMAN | G0/G1 switch regulatory protein 3 | G0S3 | Protein fosB
Type:
PROTEIN
Mol. Mass.:
35915.32
Organism:
Homo sapiens
Description:
ChEMBL_119914
Residue:
338
Sequence:
MFQAFPGDYDSGSRCSSSPSAESQYLSSVDSFGSPPTAAASQECAGLGEMPGSFVPTVTAITTSQDLQWLVQPTLISSMAQSQGQPLASQPPVVDPYDMPGTSYSTPGMSGYSSGGASGSGGPSTSGTTSGPGPARPARARPRRPREETLTPEEEEKRRVRRERNKLAAAKCRNRRRELTDRLQAETDQLEEEKAELESEIAELQKEKERLEFVLVAHKPGCKIPYEEGPGPGPLAEVRDLPGSAPAKEDGFSWLLPPPPPPPLPFQTSQDAPPNLTASLFTHSEVQVLGDPFPVVNPSYTSSFVLTCPEVSAFAGAQRTSGSDQPSDPLNSPSLLAL
  
Inhibitor
Name:
BDBM50544060
Synonyms:
CHEMBL4635546
Type:
Small organic molecule
Emp. Form.:
C16H19NO3
Mol. Mass.:
273.327
SMILES:
CCOC(=O)C1Nc2c(OC)cccc2C2C=CCC12 |c:17|
Structure:
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