Reaction Details Report a problem with these data
Target
Protein FosB
Ligand
BDBM50544065
Substrate
n/a
Meas. Tech.
ChEMBL_1991494 (CHEMBL4625229)
IC50
>100000±n/a nM
Citation
 Li, Y; Liu, Z; Aglyamova, G; Chen, J; Chen, H; Bhandari, M; White, MA; Rudenko, G; Zhou, J Discovery of phenanthridine analogues as novel chemical probes disrupting the binding of DNA to ?FosB homodimers and ?FosB/JunD heterodimers. Bioorg Med Chem Lett 30:0 (2020) [PubMed]  Article 
Target
Name:
Protein FosB
Synonyms:
FOSB | FOSB_HUMAN | G0/G1 switch regulatory protein 3 | G0S3 | Protein fosB
Type:
PROTEIN
Mol. Mass.:
35915.32
Organism:
Homo sapiens
Description:
ChEMBL_119914
Residue:
338
Sequence:
MFQAFPGDYDSGSRCSSSPSAESQYLSSVDSFGSPPTAAASQECAGLGEMPGSFVPTVTAITTSQDLQWLVQPTLISSMAQSQGQPLASQPPVVDPYDMPGTSYSTPGMSGYSSGGASGSGGPSTSGTTSGPGPARPARARPRRPREETLTPEEEEKRRVRRERNKLAAAKCRNRRRELTDRLQAETDQLEEEKAELESEIAELQKEKERLEFVLVAHKPGCKIPYEEGPGPGPLAEVRDLPGSAPAKEDGFSWLLPPPPPPPLPFQTSQDAPPNLTASLFTHSEVQVLGDPFPVVNPSYTSSFVLTCPEVSAFAGAQRTSGSDQPSDPLNSPSLLAL
  
Inhibitor
Name:
BDBM50544065
Synonyms:
CHEMBL4646481
Type:
Small organic molecule
Emp. Form.:
C14H17NO3
Mol. Mass.:
247.2897
SMILES:
COc1cccc2C3CCCC3C(Nc12)C(O)=O
Structure:
Search PDB for entries with ligand similarity: