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Target
Mu-type opioid receptor
Ligand
BDBM50547504
Substrate
n/a
Meas. Tech.
ChEMBL_2018516 (CHEMBL4672094)
Ki
>100000±n/a nM
Citation
 Arita, T; Asano, M; Kubota, K; Domon, Y; Machinaga, N; Shimada, K Discovery of DS34942424: An orally potent analgesic without mu opioid receptor agonist activity. Bioorg Med Chem 28:0 (2020) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50547504
Synonyms:
CHEMBL4754925
Type:
Small organic molecule
Emp. Form.:
C15H17FN2O
Mol. Mass.:
260.3067
SMILES:
[H][C@@]12CN(CC11CC1)Cc1cc(F)ccc1C(=O)N2C |r|
Structure:
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