Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50553404
Substrate
n/a
Meas. Tech.
ChEMBL_2046312 (CHEMBL4701011)
Ki
2498±n/a nM
Citation
 Yu, F; Zhu, C; Xie, Q; Wang, Y Adenosine A J Med Chem 63:12196-12212 (2020) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50553404
Synonyms:
CPI-444 | Ciforadenant | V-81444 | V81444
Type:
Small organic molecule
Emp. Form.:
C20H21N7O3
Mol. Mass.:
407.4258
SMILES:
Cc1ccc(o1)-c1nc(N)nc2n(Cc3cccc(CO[C@H]4CCOC4)n3)nnc12 |r|
Structure:
Search PDB for entries with ligand similarity: