Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM50553407
Substrate
n/a
Meas. Tech.
ChEMBL_2046326 (CHEMBL4701025)
IC50
<10.0±n/a nM
Citation
 Yu, F; Zhu, C; Xie, Q; Wang, Y Adenosine A J Med Chem 63:12196-12212 (2020) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM50553407
Synonyms:
CHEMBL4765154
Type:
Small organic molecule
Emp. Form.:
C23H27N5O4
Mol. Mass.:
437.4916
SMILES:
COc1ccc(N2CCOCC2)c2nc(NC(=O)c3cccc(c3)N3CCOCC3)[nH]c12
Structure:
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