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Target
Myelin-associated glycoprotein
Ligand
BDBM50556306
Substrate
n/a
Meas. Tech.
ChEMBL_2055848 (CHEMBL4710849)
Kd
56400±n/a nM
Citation
 Abdu-Allah, HHM; Wu, SC; Lin, CH; Tseng, YY Design, synthesis and molecular docking study of ?-triazolylsialosides as non-hydrolyzable and potent CD22 ligands. Eur J Med Chem 208:0 (2020) [PubMed]  Article 
Target
Name:
Myelin-associated glycoprotein
Synonyms:
GMA | MAG | MAG_HUMAN
Type:
PROTEIN
Mol. Mass.:
69048.07
Organism:
Homo sapiens (Human)
Description:
ChEMBL_770764
Residue:
626
Sequence:
MIFLTALPLFWIMISASRGGHWGAWMPSSISAFEGTCVSIPCRFDFPDELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSNVSPELGGKYYFRGDLGGYNQYTFSEHSVLDIVNTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPELSWLGHEGLGEPAVLGRLREDEGTWVQVSLLHFVPTREANGHRLGCQASFPNTTLQFEGYASMDVKYPPVIVEMNSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGTVLREAVAESLLLELEEVTPAEDGVYACLAENAYGQDNRTVGLSVMYAPWKPTVNGTMVAVEGETVSILCSTQSNPDPILTIFKEKQILSTVIYESELQLELPAVSPEDDGEYWCVAENQYGQRATAFNLSVEFAPVLLLESHCAAARDTVQCLCVVKSNPEPSVAFELPSRNVTVNESEREFVYSERSGLVLTSILTLRGQAQAPPRVICTARNLYGAKSLELPFQGAHRLMWAKIGPVGAVVAFAILIAIVCYITQTRRKKNVTESPSFSAGDNPPVLFSSDFRISGAPEKYESERRLGSERRLLGLRGEPPELDLSYSHSDLGKRPTKDSYTLTEELAEYAEIRVK
  
Inhibitor
Name:
BDBM50556306
Synonyms:
CHEMBL4780037
Type:
Small organic molecule
Emp. Form.:
C32H35N2NaO11
Mol. Mass.:
646.6169
SMILES:
[Na;v0+].[H][C@]1([#8][C@@]([#6]-[#6@H](-[#8])-[#6@H]1-[#7]-[#6](=O)-[#6]-[#8])([#8]-[#6]-c1ccccc1)[#6](-[#8-])=O)[#6@H](-[#8])-[#6@H](-[#8])-[#6]-[#7]-[#6](=O)-[#6]-c1ccc(cc1)-c1ccc(-[#8])cc1 |r|
Structure:
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