Reaction Details
Report a problem with these data
![](/images/Email.png)
Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50118964
Substrate
n/a
Meas. Tech.
ChEBML_159288
IC50
0.470000±n/a nM
Citation
![](/images/small/blackdot.gif)
More Info.:
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
Inhibitor
Name:
BDBM50118964
Synonyms:
(R)-1-[(3R,5R)-2-Hydroxy-4-(4-hydroxy-2,6-dimethyl-benzylcarbamoyl)-5-phenyl-pentyl]-4-(thiophene-2-sulfonyl)-piperazine-2-carboxylic acid tert-butylamide | CHEMBL98289
Type:
Small organic molecule
Emp. Form.:
C34H46N4O6S2
Mol. Mass.:
670.882
SMILES:
Cc1cc(O)cc(C)c1CNC(=O)[C@@H](C[C@@H](O)CN1CCN(C[C@@H]1C(=O)NC(C)(C)C)S(=O)(=O)c1cccs1)Cc1ccccc1