Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 5
Ligand
BDBM50123732
Substrate
n/a
Meas. Tech.
ChEMBL_144130 (CHEMBL750103)
Ki
260±n/a nM
Citation
 Sato, N; Takahashi, T; Shibata, T; Haga, Y; Sakuraba, A; Hirose, M; Sato, M; Nonoshita, K; Koike, Y; Kitazawa, H; Fujino, N; Ishii, Y; Ishihara, A; Kanatani, A; Fukami, T Design and synthesis of the potent, orally available, brain-penetrable arylpyrazole class of neuropeptide Y5 receptor antagonists. J Med Chem 46:666-9 (2003) [PubMed]  Article 
Target
Name:
Neuropeptide Y receptor type 5
Synonyms:
NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor
Type:
Enzyme
Mol. Mass.:
50746.64
Organism:
Human
Description:
Q15761
Residue:
445
Sequence:
MDLELDEYYNKTLATENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELQETFGSALLSSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSNKENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAPERPSQENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIKKRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLVSLIHCLHM
  
Inhibitor
Name:
BDBM50123732
Synonyms:
CHEMBL161398 | Indan-2-carboxylic acid (5-phenyl-1H-pyrazol-3-yl)-amide
Type:
Small organic molecule
Emp. Form.:
C19H17N3O
Mol. Mass.:
303.3578
SMILES:
O=C(Nc1cc(n[nH]1)-c1ccccc1)C1Cc2ccccc2C1
Structure:
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