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Target
Sentrin-specific protease 2
Ligand
BDBM50565391
Substrate
n/a
Meas. Tech.
ChEMBL_2091571 (CHEMBL4772834)
IC50
1200±n/a nM
Citation
 Wang, Z; Liu, Y; Zhang, J; Ullah, S; Kang, N; Zhao, Y; Zhou, H Benzothiophene-2-carboxamide derivatives as SENPs inhibitors with selectivity within SENPs family. Eur J Med Chem 204:0 (2020) [PubMed]  Article 
Target
Name:
Sentrin-specific protease 2
Synonyms:
KIAA1331 | SENP2 | SENP2_HUMAN | Sentrin-specific protease 2 (SENP2)
Type:
Protein
Mol. Mass.:
67890.62
Organism:
Homo sapiens (Human)
Description:
Q9HC62
Residue:
589
Sequence:
MYRWLVRILGTIFRFCDRSVPPARALLKRRRSDSTLFSTVDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVTSACNGTRNVAPSGEVFSNSSSCELTGSGSWNNMLKLGNKSPNGISDYPKIRVTVTRDQPRRVLPSFGFTLNSEGCNRRPGGRRHSKGNPESSLMWKPQEQAVTEMISEESGKGLRRPHCTVEEGVQKEEREKYRKLLERLKESGHGNSVCPVTSNYHSSQRSQMDTLKTKGWGEEQNHGVKTTQFVPKQYRLVETRGPLCSLRSEKRCSKGKITDTETMVGIRFENESRRGYQLEPDLSEEVSARLRLGSGSNGLLRRKVSIIETKEKNCSGKERDRRTDDLLELTEDMEKEISNALGHGPQDEILSSAFKLRITRGDIQTLKNYHWLNDEVINFYMNLLVERNKKQGYPALHVFSTFFYPKLKSGGYQAVKRWTKGVNLFEQEIILVPIHRKVHWSLVVIDLRKKCLKYLDSMGQKGHRICEILLQYLQDESKTKRNSDLNLLEWTHHSMKPHEIPQQLNGSDCGMFTCKYADYISRDKPITFTQHQMPLFRKKMVWEILHQQLL
  
Inhibitor
Name:
BDBM50565391
Synonyms:
CHEMBL4792569
Type:
Small organic molecule
Emp. Form.:
C29H25N3O3S2
Mol. Mass.:
527.657
SMILES:
CNc1ccc2sc(C(=O)NCc3cccc(NC(=O)c4cccs4)c3)c(OCc3ccccc3)c2c1
Structure:
Search PDB for entries with ligand similarity: