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Target
Tyrosine-protein phosphatase non-receptor type 2
Ligand
BDBM50115732
Substrate
n/a
Meas. Tech.
ChEMBL_2092037 (CHEMBL4773300)
IC50
14±n/a nM
Citation
 Lei, S; Zhang, D; Qi, Y; Chowdhury, SR; Sun, R; Wang, J; Du, Y; Fu, L; Jiang, F Synthesis and biological evaluation of geniposide derivatives as potent and selective PTPlB inhibitors. Eur J Med Chem 205:0 (2020) [PubMed]  Article 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 2
Synonyms:
PTN2_HUMAN | PTPN2 | PTPT | T-cell protein tyrosine phosphatase (TCPTP) | T-cell protein-tyrosine phosphatase | TC-PTP | TCPTP | Tyrosine-protein phosphatase non-receptor type 2 | Tyrosine-protein phosphatase non-receptor type 2 (TC-PTP)
Type:
Protein
Mol. Mass.:
48481.80
Organism:
Homo sapiens (Human)
Description:
P17706
Residue:
415
Sequence:
MPTTIEREFEELDTQRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVKLQNAENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPAFDHSPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSSKMQDTMEENSESALRKRIREDRKATTAQKVQQMKQRLNENERKRKRWLYWQPILTKMGFMSVILVGAFVGWTLFFQQNAL
  
Inhibitor
Name:
BDBM50115732
Synonyms:
CHEMBL294467 | Sodium vanadate
Type:
Small organic molecule
Emp. Form.:
O3V
Mol. Mass.:
98.9402
SMILES:
[O-][V](=O)=O
Structure:
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