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Target
D(3) dopamine receptor
Ligand
BDBM50216045
Substrate
n/a
Meas. Tech.
ChEMBL_2112627 (CHEMBL4821477)
Ki
66±n/a nM
Citation
 Ku?aga, D; Ja?kowska, J; Sata?a, G Radioligand and computational insight in structure - Activity relationship of saccharin derivatives being ipsapirone and revospirone analogues. Bioorg Med Chem Lett 42:0 (2021) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DRD3 | DRD3_HUMAN | Dopamine D3 receptor
Type:
PROTEIN
Mol. Mass.:
44213.40
Organism:
Homo sapiens
Description:
ChEMBL_105671
Residue:
400
Sequence:
MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50216045
Synonyms:
2-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-1,2-benzisothiazole-3(2H)-one 1,1-dioxide | CHEMBL394110
Type:
Small organic molecule
Emp. Form.:
C21H25N3O3S
Mol. Mass.:
399.507
SMILES:
O=C1N(CCCCN2CCN(CC2)c2ccccc2)S(=O)(=O)c2ccccc12
Structure:
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