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Target
D(1A) dopamine receptor
Ligand
BDBM50184794
Substrate
n/a
Meas. Tech.
ChEMBL_357155 (CHEMBL853175)
Ki
7500±n/a nM
Citation
 Löber, S; Hübner, H; Gmeiner, P Synthesis and biological investigations of dopaminergic partial agonists preferentially recognizing the D4 receptor subtype. Bioorg Med Chem Lett 16:2955-9 (2006) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DRD1 | DRD1_PIG | Dopamine D1 receptor
Type:
PROTEIN
Mol. Mass.:
49269.92
Organism:
Sus scrofa
Description:
ChEMBL_1460140
Residue:
446
Sequence:
MRTLNTSTMDGTGLVVERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNVTSLGKTTHNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPAECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTSTNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIASPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM50184794
Synonyms:
1-(4-Chlorophenyl)-4-[(1-phenyl-1H-pyrazol-4-yl)methyl]piperazine | 1-(4-chlorophenyl)-4-((1-phenyl-1H-pyrazol-4-yl)methyl)piperazine | CHEMBL210955
Type:
Small organic molecule
Emp. Form.:
C20H21ClN4
Mol. Mass.:
352.861
SMILES:
Clc1ccc(cc1)N1CCN(Cc2cnn(c2)-c2ccccc2)CC1
Structure:
Search PDB for entries with ligand similarity: