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Target
Target of rapamycin complex subunit LST8
Ligand
BDBM50606742
Substrate
n/a
Meas. Tech.
ChEMBL_2261204 (CHEMBL5216215)
IC50
1.000000±n/a nM
Citation
 Oleksak, P; Nepovimova, E; Chrienova, Z; Musilek, K; Patocka, J; Kuca, K Contemporary mTOR inhibitor scaffolds to diseases breakdown: A patent review (2015-2021). Eur J Med Chem 238:0 (2022) [PubMed] 
Target
Name:
Target of rapamycin complex subunit LST8
Synonyms:
G protein beta subunit-like | GBL | Gable | LST8 | LST8_HUMAN | MLST8 | Mammalian lethal with SEC13 protein 8 | Protein GbetaL | TORC subunit LST8 | Target of rapamycin complex subunit LST8
Type:
PROTEIN
Mol. Mass.:
35871.25
Organism:
Homo sapiens
Description:
ChEMBL_118692
Residue:
326
Sequence:
MNTSPGTVGSDPVILATAGYDHTVRFWQAHSGICTRTVQHQDSQVNALEVTPDRSMIAAAGYQHIRMYDLNSNNPNPIISYDGVNKNIASVGFHEDGRWMYTGGEDCTARIWDLRSRNLQCQRIFQVNAPINCVCLHPNQAELIVGDQSGAIHIWDLKTDHNEQLIPEPEVSITSAHIDPDASYMAAVNSTGNCYVWNLTGGIGDEVTQLIPKTKIPAHTRYALQCRFSPDSTLLATCSADQTCKIWRTSNFSLMTELSIKSGNPGESSRGWMWGCAFSGDSQYIVTASSDNLARLWCVETGEIKREYGGHQKAVVCLAFNDSVLG
  
Inhibitor
Name:
BDBM50606742
Synonyms:
CHEMBL5220948 | US11731973, Example 9
Type:
Small organic molecule
Emp. Form.:
C17H18N8OS
Mol. Mass.:
382.443
SMILES:
CC1(Cn2nc(-c3ccc4oc(N)nc4c3)c3c(N)nc(N)nc23)CSC1
Structure:
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