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Target
Dual specificity protein phosphatase 23
Ligand
BDBM50558488
Substrate
n/a
Meas. Tech.
ChEMBL_2262154 (CHEMBL5217165)
IC50
>200000±n/a nM
Citation
 He, R; Wang, J; Yu, ZH; Moyers, JS; Michael, MD; Durham, TB; Cramer, JW; Qian, Y; Lin, A; Wu, L; Noinaj, N; Barrett, DG; Zhang, ZY Structure-Based Design of Active-Site-Directed, Highly Potent, Selective, and Orally Bioavailable Low-Molecular-Weight Protein Tyrosine Phosphatase Inhibitors. J Med Chem 65:13892-13909 (2022) [PubMed] 
Target
Name:
Dual specificity protein phosphatase 23
Synonyms:
DUS23_HUMAN | DUSP23 | Dual specificity protein phosphatase 23 | Dual specificity protein phosphatase 23 (VHZ) | LDP-3 | LDP3 | Low molecular mass dual specificity phosphatase 3 | VH1-like phosphatase Z | VHZ
Type:
Enzyme
Mol. Mass.:
16592.49
Organism:
Homo sapiens (Human)
Description:
Q9BVJ7
Residue:
150
Sequence:
MGVQPPNFSWVLPGRLAGLALPRLPAHYQFLLDLGVRHLVSLTERGPPHSDSCPGLTLHRLRIPDFCPPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQFYQRTK
  
Inhibitor
Name:
BDBM50558488
Synonyms:
CHEMBL4794972
Type:
Small organic molecule
Emp. Form.:
C15H13Br2NO4S
Mol. Mass.:
463.141
SMILES:
Cc1c(Br)cc(NC(=O)C(c2ccccc2)S(O)(=O)=O)cc1Br
Structure:
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