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Target
Somatostatin receptor type 4
Ligand
BDBM50191272
Substrate
n/a
Meas. Tech.
ChEMBL_366815 (CHEMBL865392)
IC50
>1000±n/a nM
Citation
 Grace, CR; Erchegyi, J; Koerber, SC; Reubi, JC; Rivier, J; Riek, R Novel sst2-selective somatostatin agonists. Three-dimensional consensus structure by NMR. J Med Chem 49:4487-96 (2006) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 4
Synonyms:
SOMATOSTATIN SST4 | SS-4-R | SS4-R | SS4R | SSR4_HUMAN | SST4R | SSTR4 | Somatostatin receptor type 4 (SSTR4)
Type:
Enzyme
Mol. Mass.:
42015.38
Organism:
Human
Description:
P31391
Residue:
388
Sequence:
MSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLILSYANSCANPILYGFLSDNFRRFFQRVLCLRCCLLEGAGGAEEEPLDYYATALKSKGGAGCMCPPLPCQQEALQPEPGRKRIPLTRTTTF
  
Inhibitor
Name:
BDBM50191272
Synonyms:
CHEMBL438247 | H-c[Cys-Phe-DTrp-Lys-Thr-Cys]-OH
Type:
Small organic molecule
Emp. Form.:
C36H48N8O8S2
Mol. Mass.:
784.945
SMILES:
C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@H](NC1=O)C(O)=O
Structure:
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