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Target
Somatostatin receptor type 5
Ligand
BDBM50191270
Substrate
n/a
Meas. Tech.
ChEMBL_366816 (CHEMBL865393)
IC50
539±n/a nM
Citation
 Grace, CR; Erchegyi, J; Koerber, SC; Reubi, JC; Rivier, J; Riek, R Novel sst2-selective somatostatin agonists. Three-dimensional consensus structure by NMR. J Med Chem 49:4487-96 (2006) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 5
Synonyms:
SOMATOSTATIN SST5 | SS-5-R | SS5-R | SS5R | SSR5_HUMAN | SSTR5 | Somatostatin receptor type 5 (SSTR5)
Type:
Enzyme
Mol. Mass.:
39218.02
Organism:
Human
Description:
P35346
Residue:
364
Sequence:
MEPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADVQEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGCVRRRSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCANPVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPPAHRAAANGLMQTSKL
  
Inhibitor
Name:
BDBM50191270
Synonyms:
CHEMBL436892 | H2N-CO-DPhe-c[Cys-Aph(CONHOCH3)-DTrp-Lys-Thr-Cys]-Thr-NH2
Type:
Small organic molecule
Emp. Form.:
C52H70N14O13S2
Mol. Mass.:
1163.328
SMILES:
CONC(=O)Nc1ccc(C[C@@H]2NC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC2=O)[C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O)NC(=O)[C@@H](Cc2ccccc2)NC(N)=O)cc1
Structure:
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