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Target
Thioredoxin
Ligand
BDBM50407811
Substrate
n/a
Meas. Tech.
ChEMBL_2267400
IC50
10000±n/a nM
Citation
 Liao, M; Zhang, J; Wang, G; Wang, L; Liu, J; Ouyang, L; Liu, B Small-Molecule Drug Discovery in Triple Negative Breast Cancer: Current Situation and Future Directions. J Med Chem 64:2382-2418 (2021) [PubMed] 
Target
Name:
Thioredoxin
Synonyms:
ADF | ATL-derived factor | SASP | Surface-associated sulphydryl protein | THIO_HUMAN | TRDX | TRX | TRX1 | TXN
Type:
PROTEIN
Mol. Mass.:
11732.84
Organism:
Homo sapiens (Human)
Description:
ChEMBL_934906
Residue:
105
Sequence:
MVKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDDCQDVASECEVKCMPTFQFFKKGQKVGEFSGANKEKLEATINELV
  
Inhibitor
Name:
BDBM50407811
Synonyms:
CHEMBL5290420
Type:
Small organic molecule
Emp. Form.:
C15H9Cl2FN4
Mol. Mass.:
335.163
SMILES:
Fc1ccc(cc1)-c1ccc(Nc2nc(Cl)nc(Cl)n2)cc1
Structure:
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