Reaction Details Report a problem with these data
Target
Free fatty acid receptor 4
Ligand
BDBM50408139
Substrate
n/a
Meas. Tech.
ChEMBL_2267548
EC50
50±n/a nM
Citation
 Carullo, G; Mazzotta, S; Vega-Holm, M; Iglesias-Guerra, F; Vega-Pérez, JM; Aiello, F; Brizzi, A GPR120/FFAR4 Pharmacology: Focus on Agonists in Type 2 Diabetes Mellitus Drug Discovery. J Med Chem 64:4312-4332 (2021) [PubMed] 
Target
Name:
Free fatty acid receptor 4
Synonyms:
FFAR4 | FFAR4_HUMAN | G-protein coupled receptor 120 | G-protein coupled receptor 129 | G-protein coupled receptor GT01 | G-protein coupled receptor PGR4 | GPR120 | GPR129 | O3FAR1 | Omega-3 fatty acid receptor 1 | PGR4 | Synonyms=GPR120
Type:
PROTEIN
Mol. Mass.:
40511.04
Organism:
Homo sapiens
Description:
ChEMBL_100956
Residue:
361
Sequence:
MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIISG
  
Inhibitor
Name:
BDBM50408139
Synonyms:
CHEMBL5272316
Type:
Small organic molecule
Emp. Form.:
C24H28O3
Mol. Mass.:
364.4773
SMILES:
Cc1ccc(cc1)C1=C(COc2ccc(CCCC(O)=O)cc2)CCCC1 |c:8|
Structure:
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