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Target
Serine/threonine-protein phosphatase 5
Ligand
BDBM50408824
Substrate
n/a
Meas. Tech.
ChEMBL_2268025
EC50
1.3±n/a nM
Citation
 Zhang, Q; Fan, Z; Zhang, L; You, Q; Wang, L Strategies for Targeting Serine/Threonine Protein Phosphatases with Small Molecules in Cancer. J Med Chem 64:8916-8938 (2021) [PubMed] 
Target
Name:
Serine/threonine-protein phosphatase 5
Synonyms:
PP-T | PP5 | PPP5 | PPP5C | PPP5_HUMAN | PPT | Protein phosphatase 5 (PP5) | Protein phosphatase T | Serine/threonine-protein phosphatase 5
Type:
Enzyme
Mol. Mass.:
56875.49
Organism:
Homo sapiens (Human)
Description:
P53041
Residue:
499
Sequence:
MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM
  
Inhibitor
Name:
BDBM50408824
Synonyms:
CHAULMOOGRIC ACID | CHEBI:61391 | Chaulmoogric Acid
Type:
Small organic molecule
Emp. Form.:
C18H32O2
Mol. Mass.:
280.4455
SMILES:
OC(=O)CCCCCCCCCCCC[C@H]1CCC=C1 |r,c:18|
Structure:
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